WHY TO FAIL FAST AND OFTEN: A STRATEGY FOR OT SAFETY AND SECURITY EVALUATION




Novel Screening System of Virulent Strains for the Establishment of a Mycobacterium avium Complex Lung Disease Mouse Model Using Whole-Genome Sequencing

ABSTRACT The establishment of animal models reflecting human Mycobacterium avium complex (MAC) lung disease (LD) pathology has the potential to expand our understanding of the disease pathophysiology.However, inducing sustained infection in immunocompetent mice is difficult since MAC generally shows less virulence and higher genetic variability tha

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Deep Brain Stimulation of Medial Dorsal and Ventral Anterior Nucleus of the Thalamus in OCD: A Retrospective Case Series.

The current notion that cortico-striato-thalamo-cortical circuits here are involved in the pathophysiology of obsessive-compulsive disorder (OCD) has instigated the search for the most suitable target for deep brain stimulation (DBS).However, despite extensive research, uncertainty about the ideal target remains with many structures being underexpl

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